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Skin & Regeneration · Salmon DNA

Polynucleotides in Berlin Gently supporting skin quality

Natural portrait with fine lines and visible skin texture around the eyesSkin & Regeneration · Salmon DNA

Polynucleotides are used to support skin structure and hydration. If fine lines or dry, sensitive skin are a concern for you, I will discuss the possibilities and limitations with you. This treatment cannot replace substantial volume restoration or a surgical lift.

15–30 minstypical session lengthSkin qualityis the focusA course may be suitabledepending on your skin assessment
Costsfrom €300per treatment, depending on its scopeCosts in detailPersonal consultation

Your assessment and the scope of treatment determine your individual treatment journey.

Treatment at a glance

The treatment
at a glance

Key information about polynucleotide treatment. These details put duration, recovery and costs into context for your personal planning.

Procedure
Polynucleotide injections
Details

The product and its origin are explained in advance.

Treatment duration
Around 15–30 minutes
Details

Depending on the area, preparation and technique.

Aim
Skin structure and hydration
Details

Not a targeted treatment for substantial volume loss.

Anaesthesia
Local, if needed
Details

Depending on sensitivity and the treatment area.

Session plan
Often 2–4 sessions
Details

The spacing and number of sessions depend on the product and assessment findings.

Downtime
Varies individually
Details

Small raised bumps, swelling and bruising are possible.

Results
Develop gradually over weeks
Details

Your response and how long any effects may last cannot be predicted with certainty.

Price / pricing basis
from €300
Details

per treatment, depending on its scope. The agreed services are recorded in your personal cost plan.

Timings are a guide. A personal examination will clarify what applies to you.

Understanding what changes

What salmon DNA means
and what treatment can achieve

Polynucleotides are processed chains of DNA building blocks. In suitable formulations, they are intended to bind water and support the tissue environment. Composition, origin and application vary; I will discuss the specific product with you.

The principle behind the treatment
  1. Skin analysis

    Clarifying your concern

    Distinguishing between dryness, fine lines, pigmentation and volume loss.

  2. Application

    Choosing a suitable product

    Taking the area, tolerability and product guidelines into account.

  3. Review

    Monitoring your response

    Assessing progress before deciding on further treatments.

This principle explains the treatment. A personal examination determines which steps are medically appropriate.
How I plan your treatment

The terms ‘salmon DNA’ or, colloquially, ‘salmon sperm treatment’ are simplified descriptions of the origin of some products. No unprocessed source material is injected. Nevertheless, known fish allergies and other intolerances must be specifically discussed and assessed in relation to the product.

Research to date suggests improvements in certain skin characteristics, but is limited by small studies and differing treatment protocols. I therefore do not promise a specific rejuvenating effect or the removal of all dark circles. We agree on a clear goal and review your progress.

Putting subtle changes into perspective The treatment focuses on skin quality. Initial changes may appear after a few weeks; for some people, the effect remains small. A course or maintenance treatment is continued only where there is a demonstrable benefit.

01 / A closer lookExamining the eye area carefully

Fine lines, a deep tear trough, pigmentation and protruding fat are different findings. Polynucleotides do not remove under-eye bags. Where swelling is visible, an additional injection is not automatically advisable.

02 / A closer lookSkincare remains important

Well-tolerated skincare and suitable UV protection are part of long-term skin health. Injections do not replace these foundations. Other procedures are timed appropriately so that effects and unwanted reactions can still be assessed.

Is this right for me?

Who the treatment
may be suitable for

Your wishes are the starting point. I assess whether the findings, your health and the expected benefit align.

A possible option

When treatment may be suitable

Fine lines and declining skin quality, where there is an appropriate indication for treatment

What else matters
  • A wish for a subtle change without substantial added volume
  • Willingness to assess the benefits and limitations of a course of treatment together
Taking a closer look

What needs to be clarified beforehand

Significant excess skin, under-eye bags or substantial volume loss

What else matters
  • Assess known allergies, particularly fish allergy, in relation to the specific product beforehand
  • Active infection, an unexplained skin change, pregnancy or breastfeeding

Different causes need different solutions. Sometimes, choosing not to have a procedure is the right decision.

Compare alternatives

Eye wrinkles

Not every wrinkle under the eye needs filler. Thin, dry or sun-damaged skin, muscle movement and excess tissue require different approaches. For fine lines on the lower eyelid, skin quality and skincare may be the priority; adding volume is only an option where a separate, appropriate finding supports it.

Understand the concern in more detail

Your treatment journey

Treatment and aftercare
with personal support

  1. 01PreparationDiscussing your skin and medical history

    I ask about allergies, existing medical conditions and previous injections, and examine the planned treatment areas.

    • Explain the specific product and its origin
    • Agree on a realistic goal for your skin
  2. 02TreatmentTreating the skin

    After preparation, the product is administered using a technique suited to the product and area.

    • Local pain relief as needed
    • Allow for temporary raised bumps
  3. 03AftercareReviewing the effects

    We assess your progress and decide on further appointments or a different approach.

    • No automatic continuation of treatment indefinitely
    • Coordinate skincare and other treatments

Before you leave, we agree on how you can contact me directly for aftercare. General enquiries: team@dottore.caletti.de.

Returning to everyday life

Recovery and aftercare
with personal support

Immediately afterwardsInjection-site reactions

Small raised bumps, redness, swelling or bruising may occur and can be particularly visible around the eyes.

After a few weeksAssessing your skin's response

Changes in hydration or fine lines are reviewed after allowing some time.

After the courseReassessing the benefits

Further planning depends on your response; a fixed duration of effect has not been established.

These timeframes are a guide, not a firm promise. Your individual progress may vary.

Speaking openly about risks

Risks and limitations
considered together

Even an outpatient treatment can have unwanted consequences. Your individual risks, an appropriate indication and an achievable goal all form part of the decision.

Typical effects and reactions

  • Temporary raised bumps, redness, swelling, bruising and a feeling of pressure

Possible complications

  • Infection, an allergic reaction or a prolonged inflammatory reaction
  • Nodules and irregularities; as with injections generally, blood vessel injuries are possible
These warning signs need immediate attention

Severe or increasing pain, unusually pale or blotchy skin, or visual disturbances require immediate medical attention. If you experience visual disturbances or acute severe symptoms, call 112. Have persistent swelling or signs of inflammation checked promptly.

Understand the costs and take time to decide

Treatment costs
your individual plan

Costs depend on the product, treatment area and planned course. You will receive a breakdown before treatment begins. Following an examination and discussion, you will receive a personal cost plan.

Polynucleotides

Starting price

from €300

per treatment, depending on its scope

The agreed services are recorded in your personal cost plan.

Discuss costs in person
The price reflects your treatment plan

What influences the cost

  1. Treatment area

    The eye area, face and neck have different requirements.

  2. Product

    The product and quantity required are determined.

  3. Course of treatment

    Plan a single session, multiple appointments and later maintenance treatments separately.

Services covered by your cost planWe clarify these points in advance
  • Medical consultation and examination of the treatment area
  • The agreed procedure with a defined scope of materials and services
  • Local pain relief, if required
  • Planned reviews and personal aftercare advice

We record which services are included in the total in your individual quotation.

Additional costs & possible reimbursementConsider follow-up appointments too

A course of treatment or later maintenance treatment is not automatically included in the price of one session. Any additional diagnostic tests or corrections are also discussed separately. Please clarify any possible reimbursement with your insurer before treatment begins; aesthetic services are usually self-funded.

An examination and shared planning make the costs clear. You will receive your personal cost plan before deciding whether to proceed with treatment.

Dottore Andrea Caletti with a warm smile.

The specialist personally responsible for your care

Dottore Andrea Caletti

Specialist in Plastic and Aesthetic Surgery

Get to know me

Good to know

Frequently asked questions:
Polynucleotides

A website can offer guidance. We will discuss your personal situation during your medical consultation.

Ask your question
01

Is salmon DNA the same as polynucleotides?

The term refers to the origin of certain products. In medical terms, these are purified, processed chains of DNA building blocks. What matters is the specific product used.

02

How well have the effects been studied?

There is clinical evidence suggesting improvements in certain skin characteristics. Small studies and variations in products and protocols limit what can be predicted for an individual.

03

Can polynucleotides remove dark circles?

That depends on the cause. Pigmentation, blood vessels, loss of volume and under-eye bags each require different considerations. This treatment cannot be expected to reliably remove all dark circles.

04

How many sessions are advisable?

A course of two to four appointments is often planned. Product guidelines, your skin assessment and your response determine the number and spacing of sessions.

05

What if I have a fish allergy?

Please let me know in advance. I will check the origin and product information; depending on the risk, the product may not be suitable.

06

How much does polynucleotide treatment cost in Berlin?

Costs depend on the product, treatment area and planned course. You will receive a breakdown before treatment begins. Following an examination and discussion, you will receive a personal cost plan. Pricing basis: your individual session plan. The scope of treatment and any potential additional costs will be set out in writing before you decide.

Sources & medical background

Further medical information on the procedures described, their limitations and risks.

Contact & Directions

Any questions
before your visit?

My team will be happy to help with questions about your appointment and how to get here.

Dottore Andrea CalettiKurfürstendamm 20010719 Berlinc/o Vita Aesthetica
Dottore Andrea Caletti in a friendly conversationDottore Andrea Caletti

Let's begin with a conversation

Personal consultation
about your wishes

Tell me what matters to you.
I will take time for your questions.

Arrange a personal consultationteam@dottore.caletti.de
Polynucleotides in BerlinArrange a consultation